A review of common non-ortho-phthalate plasticizers for use
A new publication by Kambia et al. (2025) reported some evidence of co-stimulation of estrogenic and androgenic receptors by one of the minor metabolites of DOTP, 5-hydroxy mono-2-ethylhexyl terephthalate (5-OH-MEHT), but not for the other metabolites (cf. Lessmann et al., 2016 for the human metabolism of DOTP). These in vitro and in silico
CHLORINATED ESTER PLASTICIZERS - ResearchGate
Static Heat-Process Stability, Mathis Oven, 180°C for a Clear Flexible PVC Formulation 0 20 40 60 ... evaluated to find a good substitution ratio in a DOTP-based flexible formulation.
Uses of Phthalates and Other Plasticizers - U.S. Consumer
Building wire Very safe for long term use, Low volatility, low conductivity, ease of processing Higher MW plasticizers such as DIDP, DPHP, trimellitates, L911P, L11P, DTDP Low MW phthalates including DEHP, citrates, Cyclohexanoates, natural oil based Wire and Cable- other Safety is always important.
Eliminating DEHP Plasticizer in Medical-Grade PVC
Based on rodent studies thus far, DOTP appears to be the least likely of the non-phthalate alternative plasticizers to be regulated. It is also the most costefficient. While somewhat less compatible with PVC than DEHP, it processes similarly and exhibits the same level of water extractability. Citrates like ATBC are another promising alternative.
Bis(2-ethylhexyl) terephthalate
Bis (2-ethylhexyl) terephthalate commonly abbreviated DEHT (Dioctyl terephthalate or DOTP), is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. It is a non- phthalate plasticizer, being the diester of terephthalic acid and the branched-chain 2-ethylhexanol, which is referred to as octyl.
- What is the difference between a plasticizer DOP and a DOTP?
- Compared with the traditional plasticizer DOP, DOTP has less volatility loss and higher stability in long-term use, reducing material aging problems caused by plasticizer migration. High volume resistivity (up to 1×10⁹Ω-m or more), especially suitable for wire and cable insulation materials to ensure electrical safety.
- Can DOTP be used in building materials?
- Şimşek et al. added DOTP to concrete, reporting that the electrical resistance of the concrete increased with increased amounts of DOTP. They also found that DOTP could be used in building materials due to its high corrosion resistance .
- Does DOTP contain orthophthalate?
- DOTP also does not contain orthophthalate, and it is an important alternative to the carcinogenic plasticizers that do [13, 14].
- Is DOTP a suitable material for film production?
- DOTP can be a suitable material for film production due to its above-mentioned properties. Polyvinyl alcohol (PVA) is one of the preferred film-forming materials because it is non-toxic and non-carcinogenic, and has high thermal stability, high optical permeability, high flexibility and chemical resistance [, , , ].
- Does DOTP reduce the elastic modulus of DP composite film?
- However, when DOTP was used with GO in a PVA matrix, it decreased the elastic modulus of the composite film due to the agglomeration problem of the nanomaterial. The DP composite film modified with AgNPs with the highest elastic modulus was DPA7, with a 7.6 μm thickness (Fig. 5 E).
- What is DOTP used for?
- DOTP is used to produce polymer matrices in copolymers, dyes, unsaturated polyesters, polyisocyanurate foams, textile softeners, polyurethane coatings, cementitious materials [8, 11, , , , , ] and also medical devices .
