Plasticizers: Types, Uses, Classification, Selection & Regulation
Most commonly used phthalate plasticizers include: DEHP: Low molecular weight ortho-phthalate. Still the world’s most widely used PVC plasticizer DINP, DIDP: High molecular weight ortho-phthalates Aliphatic dibasic acid Esters – These include chemicals such as glutarates, adipates, azelates and sebacates.
Intravenous Admixture Compatibility for Sterile Products
Therefore, admixture stability in the syringe may only be required to be studied for shorter duration (e.g., 2–4 h at room temperature). Note that even though a syringe may be used to infuse the low volumes, it is required to be filled from an IV container containing the admixture solution of a suitable concentration.
Intravenous Admixture Compatibility for Sterile Products
Therefore, admixture compatibility and stability studies are key components of the pharmaceutical development process. On the surface these studies may seem straightforward, but in practice...
Use of Water Reducers, Retarders, and Superplasticizer
The use of WRA is defined as Type A in ASTM C 494. WRA affects mainly the fresh properties of concrete by reducing the amount of water used by 5% to 12% while maintaining a certain level of consistency, measured by the slump as prescribed in ASTM C 143-90. The use of WRA may accelerate or retard the initial setting time of concrete.
Intravenous Admixture Compatibility for Sterile Products: Challenges
465 drug product, the stability of the reconstituted drug product prior to admixture preparation may also need to be evaluated. USP ( USP 797 ) provides guidance
- What is water reducing admixture & superplasticizer?
- As one of the concrete admixtures, water reducing admixtures and superplasticizers are usually used to reduce the mixing water volume and improve the performance of the harden concrete while maintaining better workability of the fresh concrete.
- Which superplasticizer admixture is better?
- Based on the findings, out of three superplasticizers, PC—based admixture showed a better improvement in strength aspects compared to other mix. Compressive strength of UHPC (a) SNF admixture (b) SMF admixture (c) PC admixture
- What are plasticizer admixtures?
- These admixtures are known as plasticizers. The combination of organic substances or combinations of organic and inorganic substances which cause reduction in water content for a given workability or give a higher workability at the same water content are known or termed as plasticizer admixtures. These are used for the following proposes: 1.
- Can water reducing admixtures and superplasticizers be used in reinforced concrete?
- Water absorption, frost resistance and permeability resistance of the concrete are mainly reviewed to discuss this influence on the durability properties of the concrete. Then, some suggestions on the application of the water reducing admixtures and superplasticizers in reinforced concrete structures and projects are proposed.
- Does PC based admixture work in UHPC?
- Out of three superplasticizers, PC-based admixture showed a good impact with moderate workability retention and water reduction of 20–35%. The saturation dosage was attained at 1.5% of PC-based admixture. The outcome of the present study is expected to break through the fundamentals of superplasticizers and their applications in UHPC.
- What are the different types of superplasticizer admixtures?
- There is a wide variety of superplasticizer admixtures, such as lignosulphonates, naphthalene and melamine-based, vinyl copolymers and the so-called latest generation of superplasticizers, polycarboxylate derivatives.
