DEHT is a suitable plasticizer option for phthalate‐free
No individual unit exceeded 0.8% haemolysis, not even in DEHT/SAGM, the combination overall most affected by irradiation. Of the four combinations, membrane stability was least impacted in DEHP/PAGGSM. Conclusion. We demonstrate that DEHT is a suitable plasticizer for storage of RBCs after X-ray irradiation cell stress.
Analytical methods for the determination of DEHP plasticizer
It was also successfully used by Rothenbacher et al. [50] to determine if a rapid screening test for plasticizers (like DEHP, DINP, or DINCH) in PVC materials can be developed using direct analysis in real time mass spectrometry (DART-MS). An open interface would allow the direct insertion of solid specimens, such as samples of medical devices.
Leaching of the plasticizer di(2-ethylhexyl)phthalate (DEHP
Di(2-ethylhexyl)phthalate (DEHP) is a widely used plasticizer to render poly(vinyl chloride) (PVC) soft and malleable. Plasticized PVC is used in hospital equipment, food wrapping, and numerous other commercial and industrial products.
Non‐phthalate plasticizer DEHT preserves adequate blood
Polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP) has been the material of choice for commercial blood containers since the mid-20th century. Plasticizers are essential for material flexibility; facilitating centrifugation, sealing, transport and general handling of blood bags without risk of breakage and product loss
Non-phthalate plasticizer DEHT preserves adequate blood
The metabolic parameters were not influenced by choice of plasticizer. Platelet activation/metabolism and plasma content were similarly preserved. Conclusion: Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags.
- Why is DEHP used in plasticization and processing of PVC?
- The excellent performance of DEHP in the plasticization and processing of PVC explains its wide use in medical devices over the past few years. The strategy was to adjust the chemical nature of the lateral alkyl chains in order to reduce the leaching of the plasticizers into the surrounding medium.
- Is dehf a secondary plasticizer?
- An FTIR study revealed that at the relatively low contents of DEHF in the DEHF/DEHT plasticizer mixture (lower than 10/45 phr), it acted as a secondary plasticizer and dominated the interactions between PVC and DEHT.
- Which plasticizer is the most stable?
- TOTM appears to be the most stable plasticizer in short-term and long-term thermal stability studies (Fig. 2) . Fig. 2. Weight loss of traditional plasticizers (including TOTM) and ionic liquids during long-term stability of 20 wt% plasticized samples at 100 °C (from Rahman et al. ).
- How to identify alternative plasticizers?
- It is easy to obtain general information using very simple non-separative methods suitable for identifying the alternative plasticizers. These methods rely on the general features of polymers, like PVC and their plasticizers, such as thermolability and spectral and electromagnetic characteristics.
- Can poly (nadic anhydride) polyester replace DEHP in PVC films?
- In 2017, Miao et al. introduced poly (nadic anhydride) polyesters as a new plasticizer in PVC films to substitute DEHP. A series of potential plasticizers was synthesized from nadic anhydride and different polyols: 2-methyl-1,3-propanediol (P-MPO-NA), 1,4-butanediol (P-BDO-NA) and diethylene glycol (P-DEG-NA).
- Can a low molecular weight plasticizer be used as a secondary plasticizer?
- Noteworthy research focused on the introduction of a low molecular weight plasticizer as a secondary plasticizer and was carried out by Matos et al. DEHT was partially (5, 10, 15, 20 phr) replaced by di (ethylhexyl)-2,5-furandicarboxylate (DEHF) in PVC plastics (with whole plasticizer content of 55 phr).
