Bis(2-ethylhexyl) terephthalate

                                               
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Machine learning-assisted non-destructive plasticizer

                                               
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Substance Information - ECHA - Europa

                                               
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In vitro evaluation of di(2‐ethylhexyl)terephthalate

                                               
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CPSC Staff Statement on University of Cincinnati Report

                                               
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  • Is di-2-ethylhexyl terephthalate a non-Phthalate plasticizer?
  • Although di (2-ethylhexyl) terephthalate (DOTP) is being widely adopted as a non-phthalate plasticizer, existing research primarily focuses on human and rat toxicity. This leaves a significant gap in our understanding of their impact on microbial communities.
  • What is DEHT (Dioctyl terephthalate)?
  • Bis (2-ethylhexyl) terephthalate commonly abbreviated DEHT (Dioctyl terephthalate or DOTP), is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. It is a non- phthalate plasticizer, being the diester of terephthalic acid and the branched-chain 2-ethylhexanol, which is often generically referred to as octyl.
  • What is a standard state of terephthalate?
  • Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Bis (2-ethylhexyl) terephthalate commonly abbreviated DEHT (Dioctyl terephthalate or DOTP), is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2.
  • Are terephthalate plasticizers safe?
  • DEHT is a general purpose plasticizer that is considered safer than ortho - phthalate plasticizers due to its reduced toxicity profile. The terephthalates exhibit none of the peroxisome proliferation of liver enzymes that some ortho - phthalates have shown in several studies.
  • Does DOTP biodegradation affect microbes?
  • This study assessed the biodegradation and toxicity of DOTP on microbes, focusing on its impact on biofilms and microbial metabolism using Rhodococcus ruber as a representative bacterial strain. DOTP is commonly found in mass fractions between 0.6 and 20% v/v in various soft plastic products.
  • Can terephthalic acid and monoethylhexyl terephthalate be detected in the Orbitrap analysis?
  • In the Orbitrap analysis, both monoethylhexyl terephthalate and terephthalic acid were detected in samples incubated for 36 and 72 h, specifically when analyzed in positive mode. Moreover, in the 36 h sample analyzed in negative mode, monoethylhexyl terephthalate and benzoic acid were identified.