PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The mechanism of action of plasticizers is described, in terms of plasticization theory and the chemical modifications that occur during this process, which account for the excellent...
PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW
performance of some plasticizer molecules and the apparently poor softening ability of others. The current legislative and toxicological status of plasticizers is thoroughly reviewed to provide
Pharmaceutically Used Plasticizers - IntechOpen
Recent Advances in Plasticizers 46 2. Pharmaceutically used plasticizers The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993). The extent of Tg
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
Pharmaceutically Used Plasticizers. E. nejdrová, M. Dittrich. Published 21 March 2012. Materials Science, Medicine. The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers.
Pharmaceutically Used Plasticizers - ResearchGate
In the plastics industry, plasticizers have long been a popular element [2]. To name a few of its numerous applications, are automobiles, packaging, membranes, consumer goods, medicines,...
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- Why are plasticizers used in drug delivery systems?
- This is because they are incorporated into drug delivery systems containing an assortment of ingredients which may have different reactions to the presence of plasticizers. Concurrently, there are numerous pharmaceutical plasticizers and various environmental issues dictating favored solutions.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
- Why do we need plasticizers?
- 1. Introduction The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers.
- Are polymeric drug delivery systems plasticizers?
- Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
- Is hydrophilic polymer an internal plasticizer of polymeric drug delivery systems?
- As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems. In case of contact with body fluids after application the hydrophilic plasticizer can be released from polymer and thus conditions for the incorporated drug release are changed.
