Analytical methods for the determination of DEHP plasticizer
It was also successfully used by Rothenbacher et al. [50] to determine if a rapid screening test for plasticizers (like DEHP, DINP, or DINCH) in PVC materials can be developed using direct analysis in real time mass spectrometry (DART-MS). An open interface would allow the direct insertion of solid specimens, such as samples of medical devices.
Plasticiser loss from plastic or rubber products through
The plasticiser loss rate in stagnant air is approximately 1/3 of that in ventilated ageing conditions. 31 Ekelund et al. 25 reported that the DEHP evaporation rate from PVC and pure DEHP...
Widespread Plasticizer Clouds Doping Tests of Cyclists
DEHP is the primary plasticizer in many medical supplies such as IV blood bags, which are about 40 percent DEHP. But it's also in food, and diet is the largest source of DEHP exposure, said...
Effect of the Plasticizer DEHP in Blood Collection Bags on
DEHP levels in plasma collected in vacutainers were also low, although it was noted that the concentrations could reach as high as 2.6 μM. Other sources of DEHP or similar plasticizer contact are possible even in this collection method which would require further investigation, but the contamination was not nearly as significant as in the
Quantification of five plasticizers used in PVC tubing
Di-(2-ethylhexyl)-phthalate (DEHP) has been the most widely used plasticizer since its introduction in 1930. However, the non-covalent bond between DEHP (or plasticizers in general) and polymers mean they can be leached when they enter into contact with fluids containing lipophilic compounds [3].
- Is DEHP a plasticizer?
- DEHP had been used as a general-purpose plasticizer for all consumer products, including toys, food contact material, cosmetics, medical devices and household products. In 2008, it was classified as hazardous in Europe 18 and the USA, and was replaced by higher molecular weight phthalates (DINP and DIDP) as general-purpose plasticizers.
- Why is DEHP used in plasticization and processing of PVC?
- The excellent performance of DEHP in the plasticization and processing of PVC explains its wide use in medical devices over the past few years. The strategy was to adjust the chemical nature of the lateral alkyl chains in order to reduce the leaching of the plasticizers into the surrounding medium.
- Are medical devices containing DEHP Plasticized PVC safe?
- The safety of medical devices containing DEHP plasticized PVC or other plasticizers on neonates and other groups possibly at risk (2015 update). Regul. Toxicol.
- How to identify alternative plasticizers?
- It is easy to obtain general information using very simple non-separative methods suitable for identifying the alternative plasticizers. These methods rely on the general features of polymers, like PVC and their plasticizers, such as thermolability and spectral and electromagnetic characteristics.
- Do laboratory-produced PVC films have distinct patterns of DEHP release?
- A comprehensive evaluation of the laboratory-produced PVC films and commercially available PVC products revealed distinct patterns of DEHP release, thus emphasizing the role of exposure time, temperature, and solvent type in the migration process.
- What is diethylhexylphthalate (DEHP)?
- Until 2010, diethylhexylphthalate (DEHP) was the plasticizer most commonly used to soften PVC medical devices (MDs), because of a good efficiency/cost ratio. In flexible plasticized PVC, phthalates are not chemically bound to PVC and they are released into the environment and thus may come into contact with patients.
