Eastman Product List for Polymeric Plasticizers
Admex 525 is a low molecular weight, polymeric plasticizer. Admex 760 is an ultra-high molecular weight, polymeric adipate. It possesses maximum resistance to extraction, migration and volatility. Admex 770 is a medium molecular weight, polymeric adipate. It is characterized by a mild ester odor and very light color.
Topical Polymeric Films and Transdermal Patches | BASF Pharma
While topical polymeric films form intact, transparent drug delivery systems on the skin surface, transdermal patches utilize adhesive matrix technology to deliver active pharmaceutical ingredients through the skin. Due to their benefits such as physical barrier formation, ease of application, and reduced dosing frequency, topical polymeric
Exploiting Polymeric Films as a Multipurpose Drug Delivery
Polymeric films are drug delivery systems that maintain contact with the delivery tissue and sustain a controlled release of therapeutic molecules. These systems allow a longer time of drug contact with the target site in the case of topical treatments and allow the controlled administration of drugs. They can be manufactured by various methods such as solvent casting, hot melt extrusion
Film-Forming Systems in Topically Administered
Polymeric films can be previously prepared or formed in situ, after application of a film-forming system (FFS) used as a drug dosage form or to protect a dosage form or as a drug dosage form...
Preparation and evaluation of film forming polymeric
The film forming polymeric dispersions (FFPD) or film forming polymeric solutions (FFPS) are novel drug delivery systems via the skin. The formulation is composed of active ingredient, film forming agent, plasticizer, and other excipients such as penetration enhancers or solvent.
- What is a polymeric film forming system?
- Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric films in situ upon solvent evaporation. Their application convenience and cosmetic attributes, superior to conventional semi-solids, may offer improved patient compliance.
- What is a good plasticizer for biopolymer films?
- 2. Polyols such as glycerol, ethylene glycol, diethylene glycol, tri-ethylene glycol, polyethylene glycol, xylitol, sorbitol, and mannitol are considered effective plasticizers to improve the properties of biopolymer films.
- Are polymeric film-forming systems a viable alternative to steroidal analgesics?
- Such an outcome will presumably rely on the composition of the formulation. While polymeric film-forming systems (FFSs) have been used for the transdermal delivery of steroidal hormones and analgesics for systemic therapeutic effect , , , , , , , they also represent attractive, alternative topical formulations in dermatology.
- Why are plasticizers important in biopolymer-based films & coatings production?
- In biopolymer-based films and coatings production, plasticizers are also essential additives since they can improve flexibility and handling of films, maintain integrity and avoid pores and cracks in the polymeric matrix .
- What are hydrophilic plasticizers?
- This hydrophilicity can lead to an increase in WVP and a tendency of the polymer to absorb more water from the environment. Hydrophobic plasticizers, such as vegetable oils, triacetin, tributyl citrate, triethyl citrate, and fatty acids are good alternatives to solve this problem.
- Do plasticisers increase drug diffusivity in polymer films?
- Incorporation of plasticisers into the polymer films lowers the Tg, improves flexibility on the skin and, as mentioned above, is anticipated to increase drug diffusivity within, and hence release from, the film.
