Guideline on the use of phthalates as excipients in human
The high - molecular-weight phthalate polymers; CAP, HPMCP and PVAP, are polymers modified by esterification with ortho-phthalic acid groups. The phthalates restricted from toys and food articles in the EU due to evidence of endocrine disruption, have been the low -molecular weight ortho- phthalates.
Toxicity review of diethyl phthalate (DEP) - U.S. Consumer
The purity of DEP can achieve 99% or greater using current manufacturing processes (HSDB, 2009). The remaining fraction of the DEP commercial mixture can also contain impurities such as isophthalic, terephthalic acid, and maleic anhydride (Harris et al., 1997; ATSDR, 1995).
Photochemical reaction kinetics and mechanisms of diethyl
As one of phthalate esters (PAEs), diethyl phthalate (DEP) is commonly used as plasticizers for rubber, resin and plastics to improve their flexibility and softness [20]. It is widespread in the aquatic environment (freshwater, oceans and atmospheric cloud droplets) due to its huge production and intractable biodegradability [21], [22], [23].
Hazards of diethyl phthalate (DEP) exposure: A systematic
Background. Diethyl phthalate (DEP) is widely used in many commercially available products including plastics and personal care products. DEP has generally not been found to share the antiandrogenic mode of action that is common among other types of phthalates, but there is emerging evidence that DEP may be associated with other types of health effects.
Biomonitoring Summary | CDC
Diethyl phthalate (DEP) is a solvent used in many consumer products, particularly those containing fragrances. Products that may contain DEP include perfumes, colognes, deodorants, soaps, shampoos, and hand lotions. People exposed to DEP eliminate mono-ethyl phthalate (MEP) in their urine.
- Is diethyl phthalate soluble in water?
- Diethyl Phthalate (DEP) is a commonly used chemical compound, primarily known for its use as a plasticizer. It is a colorless, odorless liquid that is soluble in various organic solvents but only slightly soluble in water. DEP is produced by the esterification of phthalic anhydride with ethanol.
- What is DEP in air fresheners?
- DEP is a phthalate used in air fresheners for its syrupy consistency. There are many warnings about the use of DEP in this way as it enters our atmosphere and some studies suggest it can have harmful effects on human hormones.
- What is diethyl phthalate?
- Diethyl phthalate is a chemical compound is a diethyl ester of phthalic acid that belongs to the phthalate ester family. It is a clear, colourless liquid that is slightly denser than water and has low volatility. It is commonly synthesized via the Oxo or Ald-Ox processes and is also known as phthalol or solvanol.
- Is di-ethylhexyl phthalate a high priority chemical?
- View the supporting documents in docket EPA-HQ-OPPT-2018-0433. EPA designated di-ethylhexyl phthalate - (1,2-Benzene- dicarboxylic acid, 1,2- bis (2-ethylhexyl) ester) as a high priority chemical in December 2019 and the chemical is currently undergoing risk evaluation.
- What is the demand for diethyl phthalate in plasticizers?
- Increasing demand for diethyl phthalate in plasticizers for the manufacturing of packaging films, automotive parts, tools, and plastic films are expected to bolster the growth of the product market during the forecast period. Plastic films and bubble wraps are two common packaging materials used in the packaging industry.
- Why do companies invest in diethyl phthalate chemicals?
- Several companies are funding to expand their product portfolios of diethyl phthalate chemicals and serve a wide range of industries. Manufacturers are investing in the research and development of new and innovative products which comply with various environmental and health regulations.
