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Diisononyl Phthalate (DINP) - Proposition 65 Warnings Website

                                               
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  • Is DINP a pure substance?
  • DINP is not a pure substance, but a complex mixture containing mainly C9-branched isomers, with mean formula C26H42O4 ... /In a good quality chromatogram/ up to 40 peaks are attributed to DINP ... (37 after partial distillation) ... 5 constituents may be considered as principal (from ca 6 to ca 20%).
  • What is diisononyl phthalate (DINP)?
  • Diisononyl phthalate (DINP) has been widely used in polyvinyl chloride (PVC) products and is ubiquitous as a substitute; however, its toxicity due to exposure remains to be determined.
  • What is DINP used for?
  • DiNP is primarily used to produce flexible plastics and has replaced di-2-ethylhexyl phthalate (DEHP) in some plastics, though not in medical products. DiNP is widely used in such products as toys, flooring, gloves, drinking straws, garden hoses, and in sealants used for food packaging.
  • How is DINP produced?
  • DINP is produced by esterification of phthalic anhydride with isononyl alcohol in a closed system. Isononyl alcohol used in the synthesis of DINP is produced via ... the dimerization of butene ... . The reaction rate is accelerated by elevated temperatures (140-250 °C) and catalyst.
  • What does DINP stand for?
  • (1) National Toxicology Program; Monograph on the Potential Human Reproductive and Developmental Effects of Di-isononyl Phthalate (DINP). Oct 2000. Center for the Evaluation of Risks to Human Reproduction.
  • How is DINP metabolized?
  • In summary, in the rat, DINP was de-esterfied to the monoester, which was further metabolized by side-chain oxidation of the ester group or by hydrolysis to phthalic acid. Formation of oxidation products appeared to increase following the high dose or repeated dosing, while the hydrolysis to phthalic acid decreased.