excipients | aurorium
Our high-purity hydroxide pellets are an ideal solution where pH adjustment or caustic properties are required, yet impurities matter. Our hydroxide pellets are used in the creation of drugs such as pain relief medications, anticoagulants, and blood sugar regulators, among others. The pellet form we offer enables easier and safer handling.
Plasticizer Excipients, Inert Pharmaceutical Ingredients
Plasticizer Excipients Spectrum offers a wide range of plasticizer excipients designed to modify the physical properties of a basic polymer. Plasticizer excipients provide flexibility and permeability of the capsule film coating and are considered effective in retarding drug release in acid media.
Plasticizer Excipients | American Pharmaceutical Review
Plasticizer Excipients Plasticizers are used mainly for oral solid dosage forms. Plasticizers are added to the polymers used as film forming agents in order to make the polymer pliable and soft, enhancing the flexibility and plasticity of the films.
Plasticizer Excipients - CD Formulation
DEHP (bis (2-ethylhexyl) phthalate) is a commonly used plasticizer. It is very toxic in small doses, but long-term large-scale exposure can cause many health problems. Many tablets have film coating. This is to protect the active ingredients in the tablet. A layer of coating separates the tablet core from the outside air and humidity.
Lipid Excipients | American Pharmaceutical Review
Lipid excipients delivery the drug by creating an insoluble matrix structure from which diffusion is the principal drug release mechanism. It not only forms a water-insoluble matrix, but provides pH-independent release, non-digestible, highly resistant to physiological conditions, and does not result in alcohol-related dose dumping.
- What is a high-purity hydroxide pellet?
- Our high-purity hydroxide pellets are an ideal solution where pH adjustment or caustic properties are required, yet impurities matter. Our hydroxide pellets are used in the creation of drugs such as pain relief medications, anticoagulants, and blood sugar regulators, among others. The pellet form we offer enables easier and safer handling.
- What is a topical excipient?
- Our topical excipients include drug delivery systems, skin penetration enhancers, solubilisers, emulsifiers and emollients. Common issues affecting topical formulation include active pharmaceutical ingredient (API) instability, poor API solubilisation, and skin irritation that can lead to reduced patient compliance.
- What is a functional plasticizer?
- Our range of functional plasticizers are used in the coating of oral solid dosage forms. By improving the elasticity of the film, and modifying other physical properties, our plasticizers aid in the controlled release of active ingredients in both enteric and colonic coatings.
- Are citrate & sebacate ester plasticizers effective in aqueous coating systems?
- Our range of citrate and sebacate ester plasticizers are effective in both aqueous and solvent-based coating systems. Film permeability and drug release rate are highest with low molecular weight citrates used at high concentrations. Higher molecular weight citrates used at low concentrations provide lower permeability and slow drug release.
- What is a functional excipient used for?
- Our wide variety of functional excipients are used in oral solid dosages and injectables (vaccines, therapeutic treatments). We offer adjuvants, buffers, and plasticizers that enhance drug delivery. Our aluminum-based vaccine adjuvants enhance, accelerate, and prolong the immune response in patients during vaccination.
- Why should you use cGMP aluminum adjuvants?
- The pellet form we offer enables easier and safer handling. Adjuvants are used in vaccines to help create stronger immune responses in people receiving the vaccine. Our cGMP aluminum adjuvants enhance drug delivery and are the benchmark adjuvant in vaccine formulations.
