The Most Innovative Excipients Manufacturers and Suppliers
Ashland is a global specialty chemicals company with a long history of supplying the pharmaceutical sector with high-performance excipients and technologies. With a global manufacturing footprint, Ashland delivers high-quality products, and its scientists regularly come up with innovative technologies that support formulators and product
Plasticizer Excipients | American Pharmaceutical Review
Plasticizer Excipients Plasticizers are used mainly for oral solid dosage forms. Plasticizers are added to the polymers used as film forming agents in order to make the polymer pliable and soft, enhancing the flexibility and plasticity of the films.
Plasticizers: A Vital Excipient in Novel Pharmaceutical
plasticizer excipients. 6. Typically the plasticizers are used in the concentration of 0–20 percent w/v of dry polymer weight. However, inappropriate use of plasticizer may prompt to film breaking, splitting and peeling of the strip. 7. It is also reported that the use of certain plasticizers may
INTERNATIONAL JOURNAL PHARMACEUTICAL COMPOUNDING
COMPOUNDING SUPPORT & QUALITY CONTROL 237 Featured Excipient: Edetic Acid and Its Salts 240 Making Capsules Using a Solid Oral Dosage Form of a Different Strength Andrew Glasnapp, RPh; Yen-Tuyet-Hua 241 Calculations – Shelly J. Prince, PhD, RPh 242 Standard Operating Procedure for General Aseptic Procedures Used at a Laminar Airow Workbench
Featured excipient: Plasticizers - The Medical Dictionary
Featured excipient: Plasticizers From International Journal of Pharmaceutical Compounding, 3/1/03 by Allen, Loyd V Jr. Introduction . Plasticizers are chemicals that modify the physical properties of a basic polymer. Plasticizers are chemically and thermally stable compounds, ranging from solids to liquids.
- What are plasticizers used for in pharmaceutical manufacturing?
- In the context of pharmaceutical manufacturing, plasticizers such as TEC [ 13, 38 ], are commonly used in ASD formulations, especially in HME to reduce the process temperature [ 33] by reducing the melt viscosity [ 38 ].
- How many excipients are used in pharmaceutical products?
- In 1996, approximately 800 different excipients were used in marketed pharmaceutical products in the United States (De Jong, 1999). Excipient manufacturers usually supply their material to different end users, i.e. pharmaceuticals, food, and cosmetics.
- Which plasticizers are used in soluplus mechanical properties?
- hallate, and polyethylene glycols etc. 4.3 Poly ethylene glycolsIn another study Soluplus mechanical property was characterized with four different plasticizers. (polyethylene glycol 6, triethyl citrate, propylene glycol, and glycerin)
- Are plasticizers miscible?
- All plasticizers produced a notable reduction in the Tg of ATZ and LED suggesting miscibility. The citrate plasticizers produced a similar extent of Tg depression of around 30°C (Table II) for ATZ and 50°C for LED (Table III ).
- What is a pharmaceutical excipient?
- Excipients are low-value, high-volume products that may be used by several industries. The pharmaceutical industry, in general, is not the major customer of excipients in terms of volume supplied. It is not uncommon for the supplier to change its manufacturing process to make production more efficient, often without informing their customers.
- What is excipient quality?
- Another, aspect of excipient quality has been introduced with the ICH Q8 (R2) guideline (ICH Q8 (R2), 2009), that described the identification of critical material attributes (CMAs) for the drug substance and excipients. Variations in excipient, e.g. particle size, have therefore become an integral part of the quality by design (QbD) principles.
