PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The concentration of plasticizer affects the strength of coating films, overall integrity of drug products and drug release characteristics in therapeutic pharmaceutical dosage forms. 1, 2 The...
Pharmaceutically Used Plasticizers - IntechOpen
Recent Advances in Plasticizers 46 2. Pharmaceutically used plasticizers The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993). The extent of Tg
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
Plasticizer - an overview | ScienceDirect Topics
Plasticizers are mainly classified into five groups: phosphorated plasticizers, chloroparaffins, phthalates, adipates and sebacates The most common type is the phthalates. In particular, di-octyl phthalate (DOP) is extensively used as a plasticizer for PVC.
et al. World Journal of Biomedical and Pharmaceutical
Plasticizers are small lubricating molecules that can change polymer properties and processability. [2,3]Plasticizers are generally used to improve the mechanical properties of a polymer...
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
- Why do we need plasticizers?
- 1. Introduction The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers.
- What are the different types of plasticizers?
- This edition covers introduction and applications of various types of plasticizers including those based on non-toxic and highly effective pyrrolidones, and a new source of Collagen based bio-plasticizers that can be obtained from discarded materials from a natural source; Jumbo Squid (Dosidicus gigas).
- Are polymeric drug delivery systems plasticizers?
- Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
- Which substances were used as plasticizers?
- Oily, waxy, or fatty substances were applied as plasticizers. Other invention relates to an oral pulse release comprising a polymer micromatrix, a first active ingredient distributed substantially uniformly within polymer micromatrix and a second active ingredient deposited on the surface of the polymer matrix (Gadre et al., 2006).
