Acetyl tributyl citrate, the most widely used phthalate
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Preparation and evaluation of acetylated mixture of citrate
As an environmental bio-based plasticizer, ATMC11 was demonstrated as a biologically safe plasticizer by biological safety evaluation tests. Therefore, ATMC11 with excellent comprehensive performances and low cost can be candidate as an ideal phthalate alternative for soft PVC formulations. Introduction
Acetyl Tributyl Citrate, the Most Widely Used Phthalate
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Effect of acetylated citrate plasticizer on mechanical
The total quality of citrate and PVC was controlled at 15 g, and the mass proportion of citrate was 20 wt%, 30 wt %, 40 wt %, 50 wt % and 60 wt %, respectively ( Table S1 ). Download : Download high-res image (508KB) Download : Download full-size image Fig. 1. The detail synthetic procedure of citrate/PVC composites. 2.4. MD simulation
Plasticizing effects of citrate esters on properties of poly
Triethyl citrate (TEC) and acetyl tributyl citrate (ATBC) were used as plasticizer for poly (lactic acid) (PLA). The treated and plasticized PLA at various concentrations were analyzed by...
- Is tributyl citrate a phthalate alternative plasticizer?
- Tributyl citrate (TBC) and acetyl tributyl citrate (ATBC), as phthalate alternative plasticizers, show limited application due to low migration resistance, high volatilization rate and intense respiratory irritation.
- Can acetylated mixture of citrate esters replace phthalate plasticizers?
- In this study, we developed an effective method to synthesize acetylated mixture of citrate esters (ATMC) composed of acetyl (dibutyl-monoisooctyl) citrate, acetyl (monobutyl-diisooctyl) citrate, and a small amount of ATBC and ATOC, as an alternative for phthalate plasticizers.
- Can acetyl triethyl citrate improve tensile strength and elongation?
- Sawada et al. found that acetyl tributyl citrate (ATBC), acetyl triethyl citrate (ATEC) and triethyl citrate (TEC) and found that ATBC, ATEC and TEC could greatly improve the tensile strength and elongation at break of poly (vinylidene fluoride) (PVDF) composite .
- Does acetylation improve the plasticizing performance of citrate?
- Acetylation treatment is beneficial to improve the plasticizing performance of citrate. ATEC and ATBC have better plasticizing efficiency, and the tensile strength and elongation at break are 13.9% (18.7%) and 8.3% (2.2%) higher than that of TEC and TBC (with a citrate content of 50 wt%), respectively.
- Does acetylation affect the toxicity of citrate?
- As a plasticizer of PVC materials, the toxicity of citrate has an important impact on its wide application. In this paper, alanine was taken as the representative of protein (Fig. 14 (a)), and the interaction between TBC and ATBC and Ala was investigated to reveal the effect of acetylation treatment on the toxicity of citrate. Fig. 14.
- Can acetyl group replace hydroxyl group in PVC resin?
- MD simulation study found that the substitution of hydroxyl group with acetyl group cannot only destroy the hydrogen bond between citrate and PVC, accelerate the movement of polymer chain, increase the elasticity of PVC resin, but also reduce the binding ability of citrate and protein, and reduce its toxicity.
