PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The mechanism of action of plasticizers is described, in terms of plasticization theory and the chemical modifications that occur during this process, which account for the excellent performance
Handbook of Plasticizers - 2nd Edition - Elsevier
Description The second edition of the Handbook of Plasticizers thoroughly reviews information currently available in open literature, such as published scientific papers, information from plasticizer manufacturers, and patent literature.
Plasticizers: Types, Uses, Classification, Selection & Regulation
Plasticizers increase the flow and thermoplasticity of a polymer by decreasing the viscosity of the polymer melt, the glass transition temperature (Tg), the melting temperature (Tm) and the elastic modulus of the finished product without altering the fundamental chemical character of the plasticized material.
MECHANISMS OF PLASTICIZERS ACTION | Request PDF - ResearchGate
Plasticizer molecules swell the gel and facilitate the movement of polymer molecules, thus imparting flexibility. The lubricity and gel theories agree that plasticisers penetrate the structure of...
Pharmaceutical Applications of Plasticized Polymers - IntechOpen
soluble at pH values higher than 5.5. The addition of a plasticizer in these polymers is necessary. Methacrylic acid copolymers are available as various grades of Eudragit products. 2.1 The role of the plasticizer in the film coating The plasticizer plays the major role in the all process of the oral dosage form coating, and
- What theories explain external plasticizer action?
- Four general theories have been proposed to explain external plasticizer action. Some theories involve detailed analysis of polarity, solubility, and interaction pa-rameters and the thermodynamics of polymer behavior, whereas others treat plas-ticization as a simple lubrication of chains of polymer from each other.
- Can a plasticizer interact with a polymer?
- However, it is also important to consider the intermolecular forces between the plasticizer molecules themselves and between plasticizer and polymer. Unless all these interactions-i.e., plasticizer-plasticizer, plasticizer-polymer, and polymer-polymer-are the same order of magnitude, there can be no plasticizing action.
- What is a plasticizer in chemistry?
- "Plasticizers". In: Encyclopedia of Polymer Science and Technology Table 1. Commonly Used Plasticizers aTo convert Pa to mm Hg, divided by 133.3. bl is linear. modifying the polymer or monomer so that the flexibility of the polymer is in-creased.
- How does a plasticizer affect a polymer chain lubrication?
- Once it has penetrated the polymer the plasticizer fills free volume and provides polymer chain lubrication, increasing rotation and movement. The plasticizer content of a polymer may be increased by the suppression of crystallization in the polymer, but if crystallization subsequently occurs, the plasticizer exudes.
- What percentage of plasticizer is used by the PVC industry?
- Over 90% of the plasticizer volume is used by the PVC industry. The reason for such high usage with PVC is that the benefits imparted by the plasticization of PVC are far greater than those imparted to other polymers. PVC is the only polymer able to accept and retain large concentrations of plasticizer.
- What is a polymer plasticizer?
- plasticizer is usually defined in terms of the desired properties of a given polymer-plasticizer system. Thus, for coatings or films, it might be defined as a com pound that gives flexibility, shock resistance, hand or feel, etc.
