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  • Which solid-state plasticizers are used in a chemistry study?
  • Solubility parameters, thermal analysis, and rheological evaluation were used as assessment tools. Based on comparable solubility parameters, stearic acid, glyceryl behenate, and polyethylene glycol 8000 were selected as solid-state plasticizers.
  • What is a solid state plasticizer?
  • Based on comparable solubility parameters, stearic acid, glyceryl behenate, and polyethylene glycol 8000 were selected as solid-state plasticizers. Binary and ternary physical mixtures were evaluated as a function of plasticizer concentration for thermal and rheological behavior.
  • How can plasticizers be used to make polymers soft and flexible?
  • By adding plasticizers to compatible polymers, the materials can be modified in such a way that they become soft and flexible by decreasing their glass transition temperature. Plasticizers are classified according to their molecular structure into monomeric or polymeric types.
  • How do plasticizers affect polymers?
  • Plasticizers are substances which, by virtue of their polar or polarizable structure, weaken the secondary valence forces of polymers. By adding plasticizers to compatible polymers, the materials can be modified in such a way that they become soft and flexible by decreasing their glass transition temperature.
  • Are plasticizers miscible with API and polymer?
  • Based on the solubility parameter, plasticizers such as SA, GB, and PEG showed Δδ (API) and Δδ (polymer) < 7 MPa ½, and they are likely to be miscible with the API and polymer. These plasticizers are expected to form a one-phase system with the INM-EPO mixture.
  • What plasticizers are used in hot-melt extruded systems?
  • Although commonly used pharmaceutical plasticizers such as triacetin, 4 citrate esters, 2, 5 and lower molecular weight polyethylene glycols 2, 3, 4 have been investigated in hot-melt extruded systems, almost all of them are liquid.