Selection of Solid-State Plasticizers as Processing Aids for Hot-Melt
The objective of the study was to select solid-state plasticizers for hot-melt extrusion (HME) process. The physical and mechanical properties of plasticizers, in selected binary (polymer:plasticizer) and ternary (active pharmaceutical ingredient:polymer:plasticizer) systems, were evaluated to assess their effectiveness as processing aids for HME process.
Selection of Solid-State Plasticizers as Processing Aids for Hot-Melt
The physical and mechanical properties of plasticizers, in selected binary (polymer:plasticizer) and ternary (active pharmaceutical ingredient:polymer:plasticizer) systems, were evaluated to assess their effectiveness as processing aids for HME process.
Plasticizer efficiency | SpringerLink
(2) Taking dioctyl phthalate as the industry standard of comparison, one may express the efficiency (in %) of another plasticizer as 100 (n 0 /n 1), where n 0 is the phr of DOP required to achieve a particular Durometer value (or other desired property) and n 1 is the phr of the alternate plasticizer required to reach that same value.
Selecting Plasticizers for Adhesives and Sealants
Degradation by UV irradiation may also cause reduction of plasticizer efficiency. It has been found that plasticized PVC degrades more rapidly than unplasticized PVC in the near-UV region of the spectrum. Biodegradability: Plasticizers are used for biodegradable plastics such as polylactic acid, polycaprolactone, etc.
Phthalate-Free High Efficiency Plasticizer Improved Performance
can help to reduce plasticizer use, meet regulatory requirements and improve the environmental profile of a product while maintaining performance. Through Glass Transition Temperature (Tg) depression testing, DOWANOL LoV 485 has shown to be at least 25% more efficient than benzyl butyl phthalate. The graph below represents results
- How do you calculate plasticization efficiency?
- Primarily, plasticization efficiency is a first-order process and can be expressed as A = A 0 e − K [c] plasticizer where A = measured parameter, A 0 = A when plasticizer concentration is 0, K = rate constant, and [c] plasticizer = plasticizer concentration.
- What makes a good plasticizer?
- This limitation is particularly evident in the elevated glass transition temperatures (Tg) of PVC composites compared to conventional dioctyl phthalate (DOP) plasticizer. An ideal plasticizer should exhibit three key characteristics: (1) non-migration within the PVC matrix, (2) environmental compatibility, and (3) high plasticizing efficiency.
- What is the efficiency of the plasticizers determined by?
- Plasticizers efficiency was determined by calculating cohesive energy density, solubility parameters, free volume and interaction intensities of pristine nylon, and the nylon–plasticizer blends. Four plasticizers were studied: glycerin mono stearate, benzene sulfonamide, methyl 4-hydroxybenzoate (M4HB), and diethylhexyl phthalate.
- Are STPD plasticizers better than DOP-Plasticized PVC?
- Furthermore, when compared to DOP-plasticized PVC, it is evident that the plasticizing efficiency of STPDs, in terms of reducing the Tg of PVC, is slightly lower than that of DOP. In addition to plasticizing efficiency, good thermal stability is another critical requirement for plasticizers.
- Do Plasticizers improve formulation performance and stability?
- Although these plasticizers are effective as processing aid for HME, the effect of these plasticizers on formulation performance and stability is of utmost interest for the development of stabilized amorphous formulations. J. Swarbrick, J.C. Boylan (Eds.), Encyclopedia of Pharmaceutical Technology (19th ed.), Marcel Dekker Inc.,
- Do plasticizers affect HME process and product performance?
- Although various studies have demonstrated the effect of plasticizers on HME process and product performance, 21, 22, 23, 24, 25 no single study has investigated the systematic approach for selecting a suitable plasticizer.
