Plasticizer Excipients, Inert Pharmaceutical Ingredients
Plasticizer excipients provide flexibility and permeability of the capsule film coating and are considered effective in retarding drug release in acid media. Choose from our wide selection below, including propylene glycol, glycerin, polyethylene glycol, and much more.
Plasticizer Excipients - CD Formulation
The glycerin in water-soluble plasticizer capsules is commonly used polyethylene glycol 200, polyethylene glycol 400, propylene glycol and so on. Water-insoluble plasticizer castor oil, acetylated monoglycerides, phthalic acid esters, etc. According to chemical structure:
Plasticizer Excipients | American Pharmaceutical Review
Plasticizer Excipients Plasticizers are used mainly for oral solid dosage forms. Plasticizers are added to the polymers used as film forming agents in order to make the polymer pliable and soft, enhancing the flexibility and plasticity of the films.
Capsule Filling Excipients - CD Formulation
Application of Carrier Excipients Tablet lubricant, lipid matrix for sustained release, coating for protection and taste masking. Oral solid dosage form of direct compression, dry granulation, film coating, hot melt extrusion, rolling, spheronization, supercritical fluid extraction.
Plasticizer - Pharma Excipients
Sep 28, 2025. Highly hygroscopic pharmaceutical and nutraceutical solids are prone to significant changes in their physicochemical properties due to chemical degradation and/or solid-state transition, resulting in adverse effects on their therapeutic performances and shelf life. Moisture absorption also leads to….
- Which solid-state plasticizers are used in a chemistry study?
- Solubility parameters, thermal analysis, and rheological evaluation were used as assessment tools. Based on comparable solubility parameters, stearic acid, glyceryl behenate, and polyethylene glycol 8000 were selected as solid-state plasticizers.
- What is a solid state plasticizer?
- Based on comparable solubility parameters, stearic acid, glyceryl behenate, and polyethylene glycol 8000 were selected as solid-state plasticizers. Binary and ternary physical mixtures were evaluated as a function of plasticizer concentration for thermal and rheological behavior.
- What plasticizers are used in hot-melt extruded systems?
- Although commonly used pharmaceutical plasticizers such as triacetin, 4 citrate esters, 2, 5 and lower molecular weight polyethylene glycols 2, 3, 4 have been investigated in hot-melt extruded systems, almost all of them are liquid.
- Which reagents are used in solid-state plasticizers?
- Stearic acid (SA) (Mallinckrodt) glyceryl behenate (GB) (Gattefossé, Saint-Priest, France), and polyethylene glycol (PEG) 8000 (Dow-Union Carbide) were selected as solid-state plasticizers to be investigated. All other reagents were of analytical grade.
- Are plasticizers miscible with API and polymer?
- Based on the solubility parameter, plasticizers such as SA, GB, and PEG showed Δδ (API) and Δδ (polymer) < 7 MPa ½, and they are likely to be miscible with the API and polymer. These plasticizers are expected to form a one-phase system with the INM-EPO mixture.
- Are plasticizers effective as processing aids for HME process?
- The physical and mechanical properties of plasticizers, in selected binary (polymer:plasticizer) and ternary (active pharmaceutical ingredient:polymer:plasticizer) systems, were evaluated to assess their effectiveness as processing aids for HME process.
