Dimethyl phthalate

                                               
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Dimethyl phthalate = 99 131-11-3 - Sigma-Aldrich

                                               
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Environmental Impact on the Hypothalamus–Pituitary Axis

                                               
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Oxidative degradation/mineralization of dimethyl phthalate (DMP)

                                               
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Dimethyl Phthalate June 2008 - Australian Industrial Chemicals

                                               
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  • What is dimethyl phthalate (DMP)?
  • Dimethyl phthalate (DMP) is a member of the group of esters of phthalic acid commonly known as phthalates, used ubiquitously as solvents and plasticisers worldwide. The Phthalate Esters Panel of the American Chemistry Council (2006 revised) derived three categories of phthalates based on use, physicochemical and toxicological properties.
  • When was dimethyl phthalate declared a Priority Existing Chemical (PEC)?
  • Dimethyl phthalate (DMP) (CAS No. 131-11-3) was declared as a priority existing chemical (PEC) for public health risk assessment under the Industrial Chemicals (Notification and Assessment) Act 1989 (the Act) on 7 March 2006. The decision for declaration was based on:
  • Is DMP a LMW phthalate?
  • The NICNAS Phthalates Hazard Compendium (NICNAS 2008b) contains a comparative analysis of toxicity endpoints across 24 ortho-phthalates, including DMP. DMP has a straight carbon chain length of ≤3 and therefore is considered a LMW phthalate (refer to Section 2 for definition).
  • Is DMP a mixed phthalate plasticiser?
  • The leaching (migration) rates of DMP as a component of a mixed phthalate plasticiser (DINP+DMP) under mouthing conditions are based on those measured in human volunteers for DINP—a common primary plasticiser found in toys.
  • What is the concentration of DMP in household products?
  • Concentrations of DMP in domestic detergents, cosmetics, perfumes and personal care products are highly variable and range from 0.00004 % to 34 % (in combination with its analogue diethyl phthalate (DEP)).
  • Is DMP used in cosmetic and personal care products in Australia?
  • While it is known that DMP is used in cosmetic and personal care products in Australia, information on the DMP levels in these products is insufficient. Accordingly, the exposure estimate is based on the usage and concentration of an alternative phthalate, in this case DEP, which is commonly reported in cosmetic products in Australia.