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  • Can We quantify plasticizers in solvent mixtures with benchtop proton NMR spectroscopy?
  • The feasibility of recognizing and quantifying plasticizers in solvent mixtures with benchtop proton NMR spectroscopy and IHM was presented for the first time. For this, a methodology to quantify the absolute concentrations using IHM was introduced and validated on mixture samples.
  • Why are additives important for polymer products?
  • Hence, the production of additives such as antioxidants, organic peroxides, and plasticizers for polymer products increases as well [, , ]. Especially plasticizers are vital for almost all product formulations and account for about one-third of the total additive production .
  • Do plasticizers comply with EU regulations?
  • Compliance with EU regulations concerning plasticizer use can be checked. A novel approach is introduced for the fast, reliable, and low-cost recognition and quantification of plasticizers in plasticizers mixtures. It uses benchtop 1 H NMR spectroscopy and indirect hard modeling, a mechanistic multivariate regression technique.
  • Can a mixture of multiple plasticizers be found in commercial products?
  • However, a mixture of multiple plasticizers is usually present in most commercial products . Their molecular structure and the similarities of plasticizers typically lead to vastly complex spectral patterns and strongly overlapping peaks in mixtures, making the simplistic approach in Ref. insufficient in many cases.
  • How are hard models generated for plasticizers?
  • In this study, hard models were generated based on the Indirect Hard Modeling (IHM) approach. Hard models for each plasticizer were created from the spectra of calibration samples containing a single analyte with a concentration of about 2.5 mg mL −1.
  • Can NMR spectroscopy detect PVC plasticizers?
  • A recent study demonstrated the rapid quantification of PVC plasticizers with benchtop NMR spectroscopy working at a 40 MHz 1 H resonance frequency . With only four scans, detection limits down to 2.49 wt% of plasticizer in PVC were achieved by utilizing a simple workflow and non-deuterated solvents.