Plasticizers – Benefits, Trends, Health, and Environmental

                                               
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Plasticizers - Chemical Economics Handbook (CEH) | S&P Global

                                               
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Plasticizers: Types, Uses, Classification, Selection & Regulation

                                               
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  • Are alternative phthalate plasticizers toxic?
  • Most long-term DNELs of alternative plasticizers are relatively high compared to DEHP (one of the most toxic phthalate plasticizers). Also other phthalates (DINP, DIDP, DPHP) were less toxic than DEHP, having higher DNELs. For DBA, COMGHA, DOS and DBS no hazard was identified due to the extremely low toxicities measured.
  • Are non-phthalate plasticizers effective?
  • The response to the need for non-phthalate plasticizers that are effective, nonmigrating and nontoxic has focused on the development of plasticizing compounds derived from biomaterials or biobased materials [7 – 9]. Most often, these have been designed for use in PVC [10 – 12].
  • What are the different types of phthalate plasticizers?
  • Among them, the most common are: Phthalate Esters – Produced by esterification of phthalic anhydride or phthalic acid. Obtained by the oxidation of orthoxylene or naphthalene. Most commonly used phthalate plasticizers include: DEHP: Low molecular weight ortho-phthalate. Still the world’s most widely used PVC plasticizer
  • Are alternative plasticizers phthalate or phosphate esters?
  • Additionally, some substances are not exclusively being used as plasticizers. For example, phosphate esters have also been widely used as flame retardants (Marklund et al., 2003, Wei et al., 2015). In this work, we consider the term “alternative plasticizer” as a synonym for non-phthalate plasticizers.
  • Do alternative plasticizers metabolize phthalates and DINCH?
  • For instance, the human metabolism of phthalates and DINCH is well known. Therefore, exposure to these substances can be well assessed by measuring relevant metabolites in human matrices like blood or urine. Unfortunately, this has not been done for all relevant alternative plasticizers.
  • Which phthalates dominate the plasticizer market?
  • Chemical management varies considerably between regions and on a global scale. DEHP still dominates the plasticizer market . Therefore, target analytes were often restricted to DEHP and other LMW phthalates. House dust samples in China, for example, were strongly dominated by DEHP and DBP .