Migrability of PVC plasticizers from medical devices into a
Migrability of PVC plasticizers from medical devices into a simulant of infused solutions Medical devices (MD) for infusion and artificial nutrition are essentially made of plasticized PVC. The plasticizers in the PVC matrix can leach out into the infused solutions and may enter into contact with the patients.
Migrability of PVC plasticizers - ScienceDirect
The study of the extraction and migration of PVC plasticizers is of great importance for different reasons. Extraction of the plasticizer can occur in PVC films in contact with food, in bags or pipes in contact with biological fluids, such as blood, or even when a child could chew a PVC toy.
Migrability of PVC plasticizers from medical devices into a
The amount of the migrated plasticizer ( Qp) in the whole volume of simulant (125 mL) is determined as follow: Qp = Cp × 125. Qp is expressed in mg. Then Qp is compared with the initial weight of the PVC sample (mg). It is expressed in g of migrated plasticizer per 100 g of PVC. 3. Results 3.1. Plasticizers in PVC tubings
Migrability of pvc plasticizers | Semantic Scholar
Uses of flexible poly (vinyl chloride) (PVC) are restricted by plasticizer migration affecting material properties. Moreover, the use of phthalate-based plasticizers is being questioned worldwide… Expand 29 Migration of phthalate and non-phthalate plasticizers out of plasticized PVC films into air A. Demir, S. Ulutan Materials Science 2012
Plasticizer migration from plasticized poly(vinyl chloride
Studying DEHP migration in plasticized PVC used for blood bags by coupling Raman confocal microscopy to UV spectroscopy. Materials Science and Engineering: C2016,61 , 56-62. https://doi.org/10.1016/j.msec.2015.12.008 A. V. Dedov. Modeling the Vaporization Kinetics of a Polyvinylchloride Plasticizer. https://doi.org/10.1007/s10692-013-9500-6
- Can PVC plasticizers migrate to a polymer in contact with flexible PVC?
- The ability of different PVC plasticizers to migrate towards a polymer in contact with flexible PVC has been investigated. A procedure based on the monitoring of the plasticizer concentration by infrared spectroscopy has been employed.
- Why is plasticizer migration a problem?
- The plasticizer migration from the plastic item to its surroundings may involve the appearance of problems, namely the modification of flexibility of the PVC and the contamination of the media in contact with PVC.
- Why is extraction and migration of PVC plasticizers important?
- The study of the extraction and migration of PVC plasticizers is of great importance for several reasons. Extraction can occur in PVC films in contact with food, in bags or pipes in contact with biological fluids, such as blood, or even when a child could chew a PVC toy.
- Are PVC plasticizers harmful to patients?
- The plasticizers in the PVC matrix can leach out into the infused solutions and may enter into contact with the patients. In order to assess the risk of patient exposure to these plasticizers we evalu … Migrability of PVC plasticizers from medical devices into a simulant of infused solutions Int J Pharm.
- How can we measure plasticizer migration in coextruded PVC pipes?
- Technologically relevant for plasticizer migration studies in coextruded PVC pipes. This study introduces and validates an effective approach for monitoring the plasticizer amount and its concentration profile in polyvinyl chloride (PVC) formulations. The method combines gravimetric measurements with confocal Raman depth profiling analysis.
- Are plasticizers in the PVC matrix a risk factor for patient exposure?
- The plasticizers in the PVC matrix can leach out into the infused solutions and may enter into contact with the patients. In order to assess the risk of patient exposure to these plasticizers we evaluated the migration performance of DEHP, DEHT, DINCH, and TOTM using a model adapted to the clinical use of the MDs.
