Migrability of PVC plasticizers from medical devices into a simulant
The amount of the migrated plasticizer ( Qp) in the whole volume of simulant (125 mL) is determined as follow: Qp = Cp × 125. Qp is expressed in mg. Then Qp is compared with the initial weight of the PVC sample (mg). It is expressed in g of migrated plasticizer per 100 g of PVC. 3. Results 3.1. Plasticizers in PVC tubings
Migrability of PVC plasticizers - ScienceDirect
Nevertheless, PVC plasticizers can be released from flexible PVC in different ways [1]: (1) Volatilization from the PVC surface to the air. (2) Extraction from PVC to a liquid in contact with it. (3) Migration from PVC to a solid or semi-solid in contact with it. (4) Exudation under pressure.
Methods for determination of plasticizer migration from polyvinyl
Plasticizer migration is responsible for premature coating failure in polyvinyl chloride (PVC) synthetic materials that continue to benefit our daily life as a reliable and cost-efficient simulant of genuine leather. In this context, the establishment of standard assays that measure the migration rate of plasticizers under varying scenarios plays a pivotal role in comparing durability of those
Migrability of PVC plasticizers from medical devices into a
Migrability of PVC plasticizers from medical devices into a simulant of infused solutions Medical devices (MD) for infusion and artificial nutrition are essentially made of plasticized PVC. The plasticizers in the PVC matrix can leach out into the infused solutions and may enter into contact with the patients.
Migrability of pvc plasticizers | Semantic Scholar
Uses of flexible poly (vinyl chloride) (PVC) are restricted by plasticizer migration affecting material properties. Moreover, the use of phthalate-based plasticizers is being questioned worldwide… Expand 29 Migration of phthalate and non-phthalate plasticizers out of plasticized PVC films into air A. Demir, S. Ulutan Materials Science 2012
- Can PVC plasticizers migrate to a polymer in contact with flexible PVC?
- The ability of different PVC plasticizers to migrate towards a polymer in contact with flexible PVC has been investigated. A procedure based on the monitoring of the plasticizer concentration by infrared spectroscopy has been employed.
- Why is plasticizer migration a problem?
- The plasticizer migration from the plastic item to its surroundings may involve the appearance of problems, namely the modification of flexibility of the PVC and the contamination of the media in contact with PVC.
- How do we detect plasticizer migration from PVC synthetic materials?
- To this end, this review is compiled as a general review of the methods now available for detecting plasticizer migration from PVC synthetic materials via three different mechanisms (i.e., volatilization, exudation, and extraction), with an emphasis on the instrumentation, methodology, advantages, and limitations of each method.
- Does PBA absorption affect plasticizer migration from flexible PVC?
- Integrating the profiles in terms of weight ratios, it is found that DEHP is adsorbed 300 % more than PBA, which justifies that gravimetry is insensitive towards PBA absorption. 4. Conclusions In this study, the plasticizer migration from flexible PVC in contact with rigid PVC sheets was investigated.
- Why is extraction and migration of PVC plasticizers important?
- The study of the extraction and migration of PVC plasticizers is of great importance for several reasons. Extraction can occur in PVC films in contact with food, in bags or pipes in contact with biological fluids, such as blood, or even when a child could chew a PVC toy.
- Are PVC plasticizers harmful to patients?
- The plasticizers in the PVC matrix can leach out into the infused solutions and may enter into contact with the patients. In order to assess the risk of patient exposure to these plasticizers we evalu … Migrability of PVC plasticizers from medical devices into a simulant of infused solutions Int J Pharm.
