Diverging trends of plasticizers (phthalates and non
Background European chemicals management aims to protect human health and the environment from legacy and emerging contaminants. The plasticizer market changed in response to the restriction of low molecular weight (LMW) phthalate plasticizers such as Di (2-ethylhexyl) phthalate (DEHP) due to their hazardous properties. We investigated patterns and trends of 19 regulated and emerging
Non-phthalate plasticizer DEHT preserves adequate blood
Non-phthalate plasticizer DEHT preserves adequate blood component quality during storage in PVC blood bags Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags.
What is the best alternative to DEHP for medical-grade PVC
A monomeric plasticizer, TOTM’s high molecular weight makes it less mobile than other alternative plasticizers and, for that matter, than DEHP. In spite of its chemical designation as a terephthalate, DOTP is classified as a non-ortho-phthalate, different from DEHP in terms of animal toxicology and metabolization, explains Galland.
Eastman’s non-phthalate plasticizer is viable alternative to
Eastman’s non-phthalate plasticizer is viable alternative to DEHP for blood bags, study shows The chemicals company worked closely with the BloodCenter of Wisconsin to evaluate use of the material for blood bags, ‘one of the most challenging applications in the plastics market.’ Norbert Sparrow | Nov 15, 2016
DEHT is a suitable plasticizer option for phthalate-free
Abstract. Background and objectives: Due to increasing concerns about possible endocrine-disrupting properties, the use of the plasticizer di (2-ethylhexyl) phthalate (DEHP) will be banned in future blood storage. Di (2-ethylhexyl) terephthalate (DEHT) provides sufficient red blood cell (RBC) quality during conventional blood bank storage.
- Can alternative plasticizers replace DEHP?
- The European Commission also wanted to know about possible alternative plasticizers that can be used to replace DEHP. Consequently, eight alternative plasticizers were evaluated and among these were non phthalate plasticizers, as well as certain citrates and adipates.
- Can plasticizer DEHT replace DEHP in blood bags?
- Conclusion: Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags. Keywords: DEHP; DEHT; blood components; phthalates; plasticizers; red blood cells. © 2020 The Authors.
- Can DEHP be substituted for phthalate?
- However, given the recent European Parliament decision to prohibit the use of phthalates in cosmetics, children’s products and toys, coupled with the fact that DEHP is the only phthalate approved by the European Pharmacopoeia for medical use in PVC, the substitution of DEHP with another phthalate was not considered.13,57,58
- Are alternative plasticizers DEHP-free?
- 21 (48%) products in the NICU audit were DEHP-free; six consisted of alternative polymers and four of alternative plasticizers. Of the remaining 11 products, only three were available without DEHP at the time of the audit. Conclusion: Because of significant data gaps, systematic toxicological testing of DEHP-free alternatives is imperative.
- Are there alternatives to DEHP in NICU medical products?
- Availability of DEHP-free alternatives was determined through company websites and phone interviews. Two alternative approaches are available for replacing DEHP in NICU medical products: (1) replacement by DEHP-free plasticizers; and (2) replacement of PVC entirely through the use of other polymers.
- Does plasticizer DEHT provide adequate blood component quality?
- The metabolic parameters were not influenced by choice of plasticizer. Platelet activation/metabolism and plasma content were similarly preserved. Conclusion: Our study demonstrates that the plasticizer DEHT provides adequate blood component quality.
