Non-phthalate plasticizer DEHT preserves adequate blood
Non-phthalate plasticizer DEHT preserves adequate blood component quality during storage in PVC blood bags Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags.
Non-Phthalate Plasticizer Performs Comparably in Blood Bag Study
A recent study demonstrates that a non-phthalate plasticizer performs comparably to a phthalate plasticizer when used in red blood cell storage bags. The non-phthalate plasticizer, Eastman 168 SG, was studied at the Blood Center of Wisconsin, reported Mark Brucks, market development manager, plasticizers, for Eastman.
Non‐phthalate plasticizer DEHT preserves adequate blood
Prototype blood bags made entirely of PVC-DEHT or PVC-DEHP, respectively (including tubes, ports and filters), were manufactured for the study (Macopharma, Mouvaux, France), mimicking the commercially available quintuple bottom-and-top NPT reference (bag configuration: Supporting Information 1). Sixty-four WB units (450 ml ± 10% in 63 ml
Eastman’s non-phthalate plasticizer is viable alternative to
Eastman’s non-phthalate plasticizer is viable alternative to DEHP for blood bags, study shows The chemicals company worked closely with the BloodCenter of Wisconsin to evaluate use of the material for blood bags, ‘one of the most challenging applications in the plastics market.’ Norbert Sparrow | Nov 15, 2016
Diverging trends of plasticizers (phthalates and non
This was accompanied by their substitution with high molecular weight (HMW) phthalates and non-phthalates. HMW phthalates increased from 19% of the ∑plasticizer concentration to 46% between the mid-2000s and the late 2010s in house dust, and from 50% to 63% in SPM samples.
- Are PVC-DEHT blood bags phthalate?
- PVC-DEHT bags hold as high physical and functional quality as bags plasticized with DEHP. Therefore, we consider PVC-DEHT blood bags a recommendable non-phthalate candidate for future blood component collection and storage. Walter CW: Invention and develop-ment of the blood bag.
- Can plasticizer DEHT replace DEHP in blood bags?
- Conclusion: Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags. Keywords: DEHP; DEHT; blood components; phthalates; plasticizers; red blood cells. © 2020 The Authors.
- Does plasticizer DEHT provide adequate blood component quality?
- The metabolic parameters were not influenced by choice of plasticizer. Platelet activation/metabolism and plasma content were similarly preserved. Conclusion: Our study demonstrates that the plasticizer DEHT provides adequate blood component quality.
- Do PVC blood bags plasticized with DEHT provide adequate red blood cell quality?
- As a future aspect, the individual contribution of different pro-duction parameters should be further explored. In conclusion, this study demonstrates that PVC blood bags plasticized with DEHT provide adequate red blood cell quality during 49 days of storage.
- Are PVC-DEHT and PVC-DINCH blood bags safe for transfused patients?
- In addition to lower toxicity, transfused patients using PVC-DEHT or PVC-DINCH blood bags are less exposed to plasticizers than using PVC-DEHP bags with ranging exposure reduction from 38.9% to 87.3%, due to lower leachability into blood components. No impact of RBC storage solution on plasticizers migration.
- Does plasticizer exposure affect platelet quality?
- There were no significant differences between the properties of platelets produced in DEHT or DEHP systems (Table 3). The collective assessment of the platelet parameters demonstrated an overall high quality, independent of plasticizer exposure. No alterations in MPV were observed.
