Pharmaceutically Used Plasticizers - ResearchGate
Triethyl citrate (TEC) is used as a plasticizer for Eudragit in controlled release formulations (Wypych, 2004) and can be found specifically in the literature on EL100 films as a...
PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The concentration of plasticizer affects the strength of coating films, overall integrity of drug products and drug release characteristics in therapeutic pharmaceutical dosage forms. 1, 2 The...
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications. The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical… View via Publisher intechopen.com Save to Library Create Alert Cite
Pharmaceutically Used Plasticizers | IntechOpen
Pharmaceutically Used Plasticizers Written By Eva Snejdrova and Milan Dittrich Submitted: November 11th, 2011 Published: March 21st, 2012 DOI: 10.5772/39190 IntechOpen From the Edited Volume Recent Advances in Plasticizers Edited by Mohammad Luqman Book Details Order Print Chapter metrics overview 26,853 Chapter Downloads View Full Metrics
Pharmaceutically Used Plasticizers - IntechOpen
Recent Advances in Plasticizers 46 2. Pharmaceutically used plasticizers The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993). The extent of Tg
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
- Are polymeric drug delivery systems plasticizers?
- Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
- Where do phthalate ester plasticizers come from?
- Phthalate ester plasticizers were found to be extracted by blood from plastic tubing and from plastic bags used for blood storage. One such plasticizer was metabolized by the isolated perfused rat…
- What is a plasticizer used for?
- This particular plasticizer is characterized by good migration resistance and high thermal stability. Plastic moldings, cable sheathing and cords with a wide range of hardness and elasticity can be produced using this plasticizer. 4.1.3. Alternative plasticizers
- What are the different types of plasticizers used in polymers?
- Oily, waxy,or fatty substances were applied as plasticizers. Other i nvention polymer matrix. poly- DL -lactide- co-glycolide (PLGA) were produced. plasticizer, PEG, was added to the polymers. It was degradation-controlled phase. The plasticizer accelerated polymer. The plasticizer dep ressed the burst effect for controlled phase.