Phthalate and alternative plasticizers in indwelling medical
Phthalate and alternative plasticizers in indwelling medical devices in pediatric intensive care units - PubMed The present study aimed to identify plasticizers present in indwelling plastic medical devices commonly used in the pediatric intensive care unit (PICU).
Phthalate and alternative plasticizers in indwelling medical devices
Other plasticizers, such as di-isononyl-cyclohexane-1,2-dicarboxylate (DINCH, 2 of 97), di-isononyl phthalate (DiNP, 4 of 97), di (2-propylheptyl) phthalate (DPHP, 4 of 97) and di-isodecyl phthalate (DiDP, 2 of 97) were detected in < 5% of the investigated samples.
Phthalate and alternative plasticizers in indwelling medical devices
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Phthalate and alternative plasticizers in indwelling medical devices
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Phthalate and alternative plasticizers in indwelling medical
Other plasticizers, such as di-isononyl-cyclohexane-1,2-dicarboxylate (DINCH, 2 of 97), di-isononyl phthalate (DiNP, 4 of 97), di (2-propylheptyl) phthalate (DPHP, 4 of 97) and di-isodecyl phthalate (DiDP, 2 of 97) were detected in < 5% of the investigated samples.
- Are plasticizers present in indwelling plastic medical devices used in Picus?
- The present study aimed to identify plasticizers present in indwelling plastic medical devices commonly used in the pediatric intensive care unit (PICU). We have analyzed a wide range of medical devices (n = 97) daily used in the PICUs of two academic hospitals in Belgium and the Netherlands. Identified compounds varied between the samples.
- Do medical devices leach phthalates and alternative plasticizers?
- Most of the indwelling medical devices and essential accessories were found to actively leach phthalates and alternative plasticizers.
- Are plastic medical devices a source of phthalate exposure?
- Plastic medical devices as sources of exposure Although showing decreasing concentrations of phthalate metabolites over the previous decades and despite changing regulations (Regulation (EU), 2017), our results indicate ongoing phthalate exposure to neonates in the NICU.
- Which plasticizers are commonly used in pediatric intensive care units?
- Predominant use of DEHP as plasticizer, followed by DEHA, DEHT and TOTM. Devices containing TOTM also contained DEHP and DEHT. Only a small fraction of samples contained unidentified compounds. The present study aimed to identify plasticizers present in indwelling plastic medical devices commonly used in the pediatric intensive care unit (PICU).
- Are there alternative plasticizers in medical devices?
- In medical devices, the occurrence of alternative plasticizers is widely variable among various types of devices . Some plasticizers have specific uses, for example DINCH or ATBC are mainly used in red blood cell PVC bags due to their capacity to prevent excessive haemolysis during storage .
- Are phthalates a common plasticizer?
- Phthalates are the best-known and most widespread group of plasticizers. Human exposure to phthalates is ubiquitous and occurs from various environmental sources, including food contact materials, dust, pharmaceuticals, and household products (Panneel et al., 2021).
