Phthalate Esters Used as Plasticizers in Packed Red Blood
Phthalate esters (PE's) are plasticizers used to soften PVC-based medical devices. PE's are the most abundant man-made pollutants and increase the risk of developing an allergic respiratory...
Phthalate esters used as plasticizers in packed red blood
Phthalate esters (PE's) are plasticizers used to soften PVC-based medical devices. PE's are the most abundant man-made pollutants and increase the risk of developing an allergic respiratory disease or a malignancy. The leaching of PE's in donated packed red blood cells (PRBC) during storage was assessed.
Reduction of exposure to plasticizers in stored red blood
Di-2-ethylhexyl-phthalate is the most common plasticizer in medical devices made of polyvinylchloride and is commonly found in soft bags storing red blood cell units. Di-2-ethylhexyl-phthalate and its degradation product mono-2-ethylhexyl-phthalate can migrate into human body fluids, for example, blood and tissues.
Phthalate esters used as plasticizers in packed red blood
Phthalate esters used as plasticizers in packed red blood cell storage bags may lead to progressive toxin exposure and the release of pro-inflammatory cytokines.
Plasticizer Interaction With the Heart | Circulation
Phthalate esters used as plasticizers in packed red blood cell storage bags may lead to progressive toxin exposure and the release of pro-inflammatory cytokines. Oxid Med Cell Longev. 2009; 2:166–171. Crossref Medline Google Scholar; 43. Jaimes R, Kuzmiak-Glancy S, Brooks DM, Swift LM, Posnack NG, Kay MW.
