Phthalate plasticizer di(2‐ethyl‐hexyl) phthalate induces
The phthalate plasticizer, di (2-ethyl-hexyl) phthalate (DEHP), and its derived metabolites are common anthropogenic environmental toxins, which are known to act as endocrine disruptors. Numerous studies have associated DEHP with disruption of sex hormones, abnormal development of reproductive organs, allergies, and inflammation.
Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces
The phthalate plasticizer, di (2-ethyl-hexyl) phthalate (DEHP), and its derived metabolites are common anthropogenic environmental toxins, which are known to act as endocrine disruptors. Numerous studies have associated DEHP with disruption of sex hormones, abnormal development of reproductive organs, allergies, and inflammation.
Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces
Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells. / Wong, Jhen Hong; Wang, Yu Shiuan; Nam, Sean et al. In: Environmental Toxicology, Vol. 34, No. 11, 01.01.2025, p. 1191-1198. Research output: Contribution to journal Article peer-review
Phthalate plasticizer di(2‐ethyl‐hexyl) phthalate induces
The phthalate plasticizer, di(2‐ethyl‐hexyl) phthalate (DEHP), and its derived metabolites are common anthropogenic environmental toxins, which are known to act as endocrine disruptors.
From oxidative imbalance to compromised standard sperm
Di-(2-ethylhexyl) phthalate (DEHP) is among the most widely used plasticizers in plastic production, which has been detected in various environments. However, DEHP safety remains poorly known. Using zebrafish models, the effects of DEHP on the angiogenesis and hematopoiesis, and the underlying mechanism, were studied.
- What is di-2-ethylhexyl phthalate (DEHP)?
- Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the products.
- Is plasticizer di-(2-ethylhexyl phthalate) a endocrine disruptor?
- Plasticizer di-(2-ethylhexyl)phthalate (DEHP) is known as an endocrine disruptor and a peroxisome proliferator. A currently epidemiological study has suggested that daily high DEHP intake from phthalate-tainted foods in children may be a risk factor for renal dysfunction. DEHP can leach from medical …
- Does di-2-ethylhexyl phthalate interact with rice plants?
- Di- (2-ethylhexyl) phthalate (DEHP) as widely utilized plasticizer has aroused increasing concerns since its endocrine disrupting effects and continuous accumulation in biota. To date, the interaction mechanism between DEHP and rice plants has not been clearly illustrated at molecular level.
- Is phthalate plasticizer a endocrine disruptor?
- 7 Department of Pharmacy; Integrative Research Center in Critical Care, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. The phthalate plasticizer, di (2-ethyl-hexyl) phthalate (DEHP), and its derived metabolites are common anthropogenic environmental toxins, which are known to act as endocrine disruptors.
- How does di (2-ethylhexyl) phthalate affect follicle recruitment?
- 51.Hannon P. R., Peretz J., Flaws J. A. Daily exposure to di (2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice. Biology of Reproduction. 2014;90 (6, article no. 136) doi: 10.1095/biolreprod.114.119032.
- Does di- (2-ethylhexyl) phthalate inhibit DNA replication?
- 37.Li X., Fang E. F., Scheibye-Knudsen M., et al. Di- (2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis. Scientific Reports. 2014;4, article no. 6434 doi: 10.1038/srep06434. [DOI] [PMC free article] [PubMed] [Google Scholar]
