Plastics and cardiovascular disease | Nature Reviews Cardiology
Jaimes, R. et al. Plasticizer interaction with the heart: chemicals used in plastic medical devices can interfere with cardiac electrophysiology. Circ. Arrhythmia Electrophysiol. 12, e007294...
Plasticizer Interaction With the Heart: Chemicals Used
Heightened clinical exposure to plasticized medical products may have cardiac safety implications-given that action potential triangulation and electrical restitution modifications are a risk factor for early after depolarizations and cardiac arrhythmias. Keywords: action potentials; electrophysiology; heart; plasticizer; plastics.
Plasticizer Interaction With the Heart: Chemicals Used
Heightened clinical exposure to plasticized medical products may have cardiac safety implications—given that action potential triangulation and electrical restitution modifications are a risk factor for early after depolarizations and cardiac arrhythmias. Keywords: action potentials, electrophysiology, heart, plasticizer, plastics WHAT IS KNOWN?
Plasticizer Interaction With the Heart | Circulation
Di-2-ethylhexyl phthalate (DEHP) is the most commonly used plasticizer in Food and Drug Association–approved medical devices, including blood storage bags, tubing circuits, enteral feeding tubes, endotracheal tubes, and catheters. 4 In the finished product, DEHP can contribute up to 40% by weight in intravenous bags and 80% by weight in medical
Phthalate MEHP and cardiac arrhythmias -- ScienceDaily
A preclinical study, entitled "Plasticizer Interaction With the Heart," appears in the July issue of Circulation: Arrhythmia and Electrophysiology and examines the role plastic exposure, akin...
- Can plasticizers interfere with cardiac electrophysiology?
- Jaimes, R. et al. Plasticizer interaction with the heart: chemicals used in plastic medical devices can interfere with cardiac electrophysiology. Circ. Arrhythmia Electrophysiol. 12, e007294 (2019). The author is supported by the NIH (R01HL139472) and the Children’s Heart Institute.
- Are plasticizers a risk factor for cardiac arrhythmias?
- Heightened clinical exposure to plasticized medical products may have cardiac safety implications-given that action potential triangulation and electrical restitution modificationsare a risk factor for early after depolarizations and cardiac arrhythmias. Keywords: action potentials; electrophysiology; heart; plasticizer; plastics.
- Are Plasticizer additives harmful to humans?
- Plastics are indispensable materials; however, their ubiquity has raised concerns about the continuous exposure of humans to plastics. To date, these concerns are primarily directed towards plasticizer additives, such as di (2-ethylhexyl) phthalate (DEHP) and synthetic chemicals used to create polymers, such as bisphenol A (BPA).