A Strategy for Nonmigrating Highly Plasticized PVC - Nature
Nonmigrating highly plasticized PVC was prepared based on a new compound that acts as a plasticizer that was derived from di (2-ethylhexyl) 4-hydrophthalate and chlorinated paraffin-52. The...
Prevention of plasticizer leaching from PVC medical devices
These hybrids were used as coatings for flexible PVC tubes in order to reduce the plasticizer leaching from PVC medical devices. Extraction tests carried out with hexane indicated that all coating composition investigated are able to strongly reduce (about one order of magnitude) the leaching of di-ethylhexyl phthalate in hexane.
Photoreactive Carboxybetaine Copolymers Impart
Furthermore, the polymer effectively prevented leaching of plasticizers out from commercial medical-grade PVC materials. This coating technique is readily applicable to many other polymers and medical devices requiring surfaces that will enhance performance in clinical settings.
Prevention of plasticizer leaching from PVC medical devices
These hybrids were used as coatings for flexible PVC tubes in order to reduce the plasticizer leaching from PVC medical devices. Extraction tests carried out with hexane indicated that all coating composition investigated are able to strongly reduce (about one order of magnitude) the leaching of di-ethylhexyl phthalate in hexane. The best
Materials degradation in PVC medical devices, DEHP leaching
At room temperature PVC is hard and brittle, thus great amounts (40-50%) of phthalate esters that act as plasticizers are added to the polymer to make it flexible and appropriate for medical use. Di-(2-ethylhexyl)-phthalate (DEHP) is the most widely used plasticizer in PVC medical devices.
- Why are PVC medical devices so popular?
- Since then, PVC medical devices have become ubiquitous thanks to their light weight, softness, low manufacturing cost, transparency, recyclability, water and chemical resistance and resilience , . However, to make PVC soft and flexible, PVC must be mixed with plasticizers.
- Can phthalates be used if PVC plastic is leaking?
- Therefore, phthalates might be still used, but its leaking or migration should be prevented. A coating on the surface of PVC was reported to isolate plasticizer from the environment and prevent the leaking of phthalate from PVC plastics 28 – 31.
- Is Plasticized PVC good for long-term use?
- Internally plasticized PVC can maintain its performance over long-term use because there is no plasticizer migration. However, internal plasticization is less efficient and generally has an unsatisfactorily narrow use temperature range.
- Why is plasticizer important?
- Plasticizer is not only a processing aid but also an important component to determine the performance and application of PVC. Therefore, plasticizers are the most important commercial application of PVC. However, plasticizers can leach out of flexible PVC, changing the performance of PVC with age and contaminating the environment.
- What is the energy gain of plasticizer leaching?
- If we assume that half of the solvation layer is recovered during the migration into bulk solution, the plasticizer leaching allows an energetic gain between -44 and -33 kJ mol −1 in water and between -59 and -49 kJ mol −1 in ethanol. In the water-ethanol mixture, the gain ranges from -64 to -47 kJ mol −1. Fig. 6.
- Do plasticizers migrate from PVC surfaces?
- Long duration simulations showed plasticizer migration from PVC surfaces. Plasticizer migration was characterized and explained from a thermodynamic perspective. Molecular simulations helped rationalize the impact of solvents on the interactions. The adsorption of an active substance was function of the interface properties.
