Acetyl tributyl citrate, the most widely used phthalate substitute
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Acetyl Tributyl Citrate (ATBC) - Chemical Supplier
Application. Acetyl Tributyl Citrate (ATBC) is used as a biodegradable plasticizer for PVC and cellulose derivates, and it is approved for food contact materials and can even be used as a food additive. ATBC is also used as an emollient for personal care/cosmetics products such as aerosol hair sprays and nail polishes.
Acetyl Tributyl Citrate, the Most Widely Used Phthalate Substitute
We then focused on acetyl tributyl citrate (ATBC) (CAS no. 77-90-7; empirical formula, C 20 H 34 O 8; MW, 402.5; Fig. 1), which showed the strongest effect on SXR-mediated transcription. The response to ATBC in various species was evaluated by a reporter assay, and tissue-specific ATBC effects were assessed in liver and intestinal cells.
Analysis of the most appropriate risk management option (RMOA) - Europa
tributyl ester Acetyl tributyl citrate Type of substance Mono-constituent Multi-constituent UVCB Structural formula: 1.2 Similar substances/grouping possibilities The tributyl citrate (TBC, EC No 201-071-2) registrant proposed in its dossier a category approach with TEC, ATEC, ATBC and ATEHC (see FR RMOA on TBC). The read-
Method to analyze phthalate esters from soft toys
Considering the harmful effects of PAEs, alternatives such as dioctyl terephthalate (DOTP), acetyl tributyl citrate (ATBC), and 1,2-cyclohexanedicarboxylic acid diisononyl ester (DINCH) have been developed. Download : Download high-res image (461KB) Download : Download full-size image; Fig. 1.
- What is acetyl tributyl citrate (ATBC)?
- ATBC, Acetyl Tributyl Citrate, CAS: 77-90-7, is a plasticizer which can easily substitute those plasticizers to be phased out by the EU by February 2015. Actually, one of the main ATBC application is substitution of Phthalates plasticizers (Acetyl Tributyl Citrate is a Phthalate-FREE, bio based plasticizer).
- Where can I find information about acetyl tributyl citrate?
- Approved in the USA for direct food contact in food films. J & K SCIENTIFIC LTD. Acetyl tributyl citrate (CAS 77-90-7) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
- How do you store acetyl tributyl citrate?
- n 20/D 1.443 (lit.) storage temp. Store below +30°C. Not miscible with water, miscible with ethanol (96 per cent) and with methylene chloride. clear colorless liquid Acetyltributyl citrate is a clear, odorless, practically colorless, oily liquid. Acetyl tributyl citrate (ATBC) is a colorless, odorless liquid.
- What is acetyltributyl citrate used for?
- Acetyltributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings, including capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release and enteric formulations. When heated to decomposition it emits acrid smoke and irritating fumes.
- What is ATBC resin?
- ATBC is an organic origin mono constituent substance; their solvent power ensures compatibility with all resins improving the dissolution of the blend. ATBC is a plasticizer that has a high boiling point and molecular weight; there is not loss volatility. ATBC is a product with high resistance to light and heat.
- What does tributyl 2-acetylcitrate taste like?
- An emulsion of the title material in water at 1000 ppm has only a very faint, mildly fruity-winey, berry-like odor and a mild, nondescript taste. Tributyl 2-acetylcitrate is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid.
