Quantification of five plasticizers used in PVC tubing
Quantification of five plasticizers used in PVC tubing through high performance liquid chromatographic-UV detection Authors Tsanta Radaniel 1 , Stéphanie Genay 2 , Nicolas Simon 3 , Frédéric Feutry 1 , Francesca Quagliozzi 1 , Christine Barthélémy 1 , Marie Lecoeur 4 , Valérie Sautou 5 , Bertrand Décaudin 2 , Pascal Odou 2 , ARMED study group
Quantification of five plasticizers used in PVC tubing
Each length of PVC tubing contained one plasticizer with the following amounts: 32, 34, 31, 29 and 36% (w/w) for ATBC, DEHP, DEHT, DINCH and TOTM, respectively. Plasticizers were extracted according to a previously published method [17].
Quantification of five plasticizers used in PVC tubing
Quantification of five plasticizers used in PVC tubing through high performance liquid chromatographic-UV detection Author links open overlay panel Tsanta Radaniel a b , Stéphanie Genay a b c , Nicolas Simon a b c , Frédéric Feutry a b , Francesca Quagliozzi a b , Christine Barthélémy a b , Marie Lecoeur a d , Valérie Sautou e f
Quantification of five plasticizers used in PVC tubing
Five plasticizers, acetyl tributyl citrate, di- (2-ethylhexyl)-phthalate, di- (ethylhexyl)-terephthalate, di-isononyl-1,2-cyclohexane-dicarboxylate, and trioctyl trimellitate, were separated on...
Liquid chromatography-tandem mass spectrometric analysis
In the manufacturing process of plastic products using polyvinyl chloride (PVC), plasticizers are generally used to make the products flexible and durable. The most commonly used PVC plasticizers are phthalate esters, such as bis (2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP).
- What are the limits of quantification of PVC plasticizers?
- The reported limits of quantification were 5 μg/mL and 25 ng/mL, respectively. After extraction from PVC tubes by diluting with THF and precipitating PVC with ethanol, the plasticizers were quantified by GC–MS with high sensitivity (LOD between 0.06 and 0.25 μg/mL and LOQ between 0.01 and 2.0 μg/mL, depending on the plasticizer).
- How many plasticizers are in each length of PVC tubing?
- Each length of PVC tubing contained one plasticizer with the following amounts: 32, 34, 31, 29 and 36% (w/w) for ATBC, DEHP, DEHT, DINCH and TOTM, respectively. Plasticizers were extracted according to a previously published method .
- How are plasticizers extracted from PVC-tubing?
- Plasticizers were extracted from PVC-tubing by dissolving PVC in THF then precipitating it in methanol with a yield of over 90% for each plasticizer. This assay could feasibly be used to quantify plasticizers in PVC medical devices. 1. Introduction
- Can plasticizers be quantified in a general collection of degraded PVC objects?
- Additionally, regression models for quantification of di (2-ethylhexyl) phthalate and di (2-ethylhexyl) terephthalate in PVC were built. This study of real-life objects demonstrates that classification and quantification of plasticizers in a general collection of degraded PVC objects is possible, providing valuable data to collection managers.
- How much plasticizer can be detected in PVC?
- With only four scans, detection limits down to 2.49 wt% of plasticizer in PVC were achieved by utilizing a simple workflow and non-deuterated solvents. This detection limit was only three times larger than in a comparative high-field NMR spectroscopy study [38, 51].
- Can plasticizers be used in proton NMR spectra?
- The approach is demonstrated on five different PVC plasticizers having similar spectral signatures in proton NMR spectra. With only 16 scans per spectrum, i.e., 2 min 40 s measurement time, quantification limits down to 0.14 mg mL −1, or 0.35 wt% plasticizer in PVC, were achieved.
