Pilot study on novel blood containers with alternative plasticizers
Here, we compared the red blood cell preservation ability of two types of non-DEHP blood containers with safe alternative plasticizers to that of DEHP blood containers. Red cell concentrates in mannitol-adenine-phosphate solution (MAP/RCC) were stored for 6 weeks in PVC blood bags containing DEHP, di-isononyl-cyclohexane-1,2-dicarboxylate
Searching for Alternative Plasticizers for Red Blood Cell Storage Bags
Searching for Alternative Plasticizers for Red Blood Cell Storage Bags October 15, 2015 By Deb Chen, PhD Candidate in Devine Lab, CBR Image by Deb Chen Polyvinyl chloride, commonly abbreviated as PVC, is a plastic polymer widely used in medical device production.
DEHP plasticizer and blood bags: challenges ahead
properties found for red blood cells (RBC), the toxicology and the potential alternative being currently searched. PVC-DEHP and red blood cells Plastic materials are based on polymers, which are large molecules built up by the repetition of small, simple chemical units (monomers). Polymers alone are of little
Pilot study on novel blood containers with alternative plasticizers
Di (2-ethylhexyl) phthalate (DEHP), a typical plasticizer used for polyvinyl chloride (PVC) blood containers, is eluted from the blood containers and exerts protective effects on red blood cells. However, a concern for detrimental effects of DEHP on human health has led to the development of potential DEHP substitutes. Here, we compared the red blood cell preservation ability of two types of
Commercially available blood storage containers - PubMed
Specific issues addressed included the use of di-ethylhexyl phthalate (DEHP) as plasticizer for polyvinyl chloride (PVC) blood bags, the size, material and thickness of platelet bags, and the fracture resistance of plasma bags. Alternatives to DEHP for red blood cell (RBC) storage exist, but are mostly in a developmental stage.
