Simultaneous determination of polyvinylchloride plasticizers di(2
Simultaneous analysis of acidic and neutral analytes by MS/MS potential switching. Di (2-ethylhexyl) phthalate (DEHP) and tri (2-ethylhexyl) trimellitate (TEHTM or TOTM) are common plasticizers that are also largely used for PVC medical devices, e.g. bags and tubing for blood transfusions and infusions.
Simultaneous determination of polyvinylchloride plasticizers di(2
Simultaneous determination of polyvinylchloride plasticizers di (2-ethylhexyl) phthalate and tri (2-ethylhexyl) trimellitate and its degradation products in blood by liquid chromatography-tandem mass spectrometry - ScienceDirect Journal of Chromatography A Volume 1410, 4 September 2015, Pages 173-180
Simultaneous determination of polyvinylchloride plasticizers di(2
Simultaneous determination of polyvinylchloride plasticizers di (2-ethylhexyl) phthalate and tri (2-ethylhexyl) trimellitate and its degradation products in blood by liquid chromatography-tandem mass spectrometry Epub 2015 Jul 26. Authors Elisabeth Eckert 1 , Johannes Müller 1 , Thomas Gen 2 Affiliations
Simultaneous and sensitive determination of the main metabolites of the
Therefore, an on-line SPE-LC-MS/MS method for the simultaneous determination of the most relevant urinary biomarkers of exposure to DEHP and the alternative plasticizers 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH), di-(2-ethylhexyl) terephthalate (DEHTP) and tri-(2-ethylhexyl) trimellitate (TEHTM) was developed.
New SPE-LC-MS/MS method for the simultaneous determination in urine
Simultaneous determination of polyvinylchloride plasticizers di (2-ethylhexyl) phthalate and tri (2-ethylhexyl) trimellitate and its degradation products in blood by liquid chromatography-tandem mass spectrometry J. Chromatogr. A (2015) M.J. Silva et al.
- How to analyze PVC plasticizer DEHP & TOTM in human blood?
- The developed analytical procedure enables the simultaneous determination of the common PVC plasticizer DEHP and its substitute TOTM in human blood using LC–MS/MS analysis following liquid–liquid extraction. At the same time, the degradation products MEHP, 2-MEHTM and 1,2-DEHTM can be determined.
- How to evaluate volatilization propensity of plasticizers from PVC synthetic materials?
- Currently, the most commonly employed methods that enable quantitative evaluation of the volatilization propensity of plasticizers from PVC synthetic materials are fogging test and activated carbon method.
- How do we detect plasticizer migration from PVC synthetic materials?
- To this end, this review is compiled as a general review of the methods now available for detecting plasticizer migration from PVC synthetic materials via three different mechanisms (i.e., volatilization, exudation, and extraction), with an emphasis on the instrumentation, methodology, advantages, and limitations of each method.
- Can LC-MS detect plasticizer metabolites in human urine?
- This new LC-MS/MS sensitive method has been developed for the rapid and simultaneous detection and quantification of plasticizer metabolites in human urine. Except for DEHA, these metabolites are specific biomarkers of the exposure to DEHP-alternative plasticizers that are contained in MD.
- How to compare plasticizer volatilization from PVC?
- Thus, some practitioners refer to follow ISO176:2005 (E) that specifies an economically accessible method, intended for a rather rapid comparison of plasticizer volatilization from PVC in the presence of activated carbon. In this method, the PVC synthetic materials are cut into discs of 50 mm ± 1 mm in diameter and 1 mm ± 0.1 mm in thickness.
- Do plasticizers migrate from PVC?
- These additives are supposed to stay in PVC for permanent flexibility, but unfortunately, they continue migrating from the coating matrix, leading to a series of consequences. A range of analytical methods for the determination of plasticizer migration from PVC synthetic materials is now available.
