The influence of plasticizers on the release of theophylline
The influence of plasticizer on the release of theophylline from microporous-controlled tablets was demonstrated. The fatty plasticizer, castor oil, altered the thermal and mechanical performance and pore size of microporous films via soluble in PCL domain, which resulted in the release of theophylline from plasticized-coated tablets, which in turn enhanced and closed to a constant release
The influence of plasticizers on the release of theophylline
The aim of present work was to investigate the influence of plasticizer on the release of theophylline from microporous-controlled tablets. Three plasticizers, acetyltributyl citrate (ATBC), castor oil, and triacetin, were included in this study.
The influence of plasticizers on the release of theophylline
Abstract The aim of present work was to investigate the influence of plasticizer on the release of theophylline from microporous-controlled tablets. Three plasticizers, acetyltributyl citrate (ATBC), castor oil, and triacetin, were included in this study.
The influence of plasticizers on the release of theophylline
The influence of plasticizers on the release of theophylline from microporous-controlled tablets. ... Citations & impact Similar Articles
The influence of plasticizers on the release of Theophylline
The fatty plasticizer, castor oil, altered the thermal and mechanical performance and pore size of films via soluble in PCL domain, which resulted in the release of theophylline from castor...
- Does plasticization time affect drug release?
- In contrast, with the water-insoluble plasticizer acetyltributyl citrate (ATBC), plasticization time (1/2 h vs 24 h) influenced the drug release, the longer plasticization time resulted in a slower drug release because of a more complete plasticizer uptake prior to the coating step.
- How does plasticizer content affect drug release profiles?
- The release profiles of TH from the coated pellets were influenced by the type and amount of plasticizer and of coating material, and by the ratio polymer-plasticizer. For both types of coating, the drug release rate decreased with increasing plasticizer content.
- Why are plasticizers added to the polymer coating of sustained-release granules?
- Plasticizers are added to the polymer coating of sustained-release granules to improve the mechanical properties of the coating shell.
- Which plasticizers are present in coating films?
- The plasticizers, present in the coating films in amounts ranging from 8 to 30%, were acetylated monoglycerides (AMG), diethyl phthalate (DEP), dibutyl phthalate (DBP) and dibutyl sebacate (DBS).
