Film-Forming Systems in Topically Administered
Polymeric films can be previously prepared or formed in situ, after application of a film-forming system (FFS) used as a drug dosage form or to protect a dosage form or as a drug dosage form...
Topical Polymeric Films and Transdermal Patches | BASF Pharma
Develop a broad range of topical polymeric films and transdermal patches with our diverse selection of film formers, matrix formers, plasticizers, and solvents. Explore Our Diverse Product Portfolio Kollicream Mild emollients aiding in the dermal penetration of active ingredients View products Kollisolv
TEC Plasticization of Topical Polymeric Films | SpringerLink
The degree of homogeneity and the mechanical properties of topical polymeric films for drug delivery are vital to their efficacy. The dispersal of plasticizer and the solubility of the drug within the films (the homogeneity of their distribution) affect their function; phase separations have been shown to trigger drug crystallization [] and the efficacy (bioavailability) and stability of the
Special Issue "Green Plasticizers for Polymers" - MDPI
The scope of this issue ranges from synthesis of green plasticizers, enhancement of physical and rheological properties, migration of plasticizers upon disposal, relationships between plasticizers and human health, and life-cycle-assessment.
Plasticizers in Transdermal Drug Delivery Systems - ResearchGate
The commonly used plasticizers in dermal delivery patches include phthalate esters, phosphate esters, fatty acid esters and glycol derivatives (Gngr et al., 2012; Lim and Hoag, 2013). In this...
- Why are plasticizers used in film forming systems?
- Plasticizers Plasticizers are used in the film forming systems to impart flexibility to the film and improve the tensile strength of the film formed. The plasticizer used should be compatible with the polymers used and should have low skin permeability.
- What is a topical film forming system?
- Topical film forming systems are such developing drug delivery systems meant for topical application to the skin, which adhere to the body, forming a thin transparent film and provide delivery of the active ingredients to the body tissue.
- What is a polymeric film forming system?
- Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric films in situ upon solvent evaporation. Their application convenience and cosmetic attributes, superior to conventional semi-solids, may offer improved patient compliance.
- Are polymeric film-forming systems a viable alternative to steroidal analgesics?
- Such an outcome will presumably rely on the composition of the formulation. While polymeric film-forming systems (FFSs) have been used for the transdermal delivery of steroidal hormones and analgesics for systemic therapeutic effect , , , , , , , they also represent attractive, alternative topical formulations in dermatology.
- Do plasticisers increase drug diffusivity in polymer films?
- Incorporation of plasticisers into the polymer films lowers the Tg, improves flexibility on the skin and, as mentioned above, is anticipated to increase drug diffusivity within, and hence release from, the film.
- Which polymers are plasticized?
- The plasticizers produced have been applied in 60 polymers and more than 30 groups of products. Industrially, the most common plasticized polymers are PVC, poly (vinyl butyral) (PVB), poly (vinyl acetate) (PVAc), acrylics, cellulose molding compounds, nylon, polyamides and certain copolyamides.
