Phthalate and novel plasticizer concentrations in food items
High molecular weight phthalates like di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) are commonly used as plasticizers in polyvinyl chloride (PVC) materials such as food
[Toxicity effects of phthalate substitute plasticizers used
In the present review, the toxicity information on 6 alternatives to phthalate plasticizers is summarized, focusing on the effects after oral exposure, which is the route of most concern. Publication types English Abstract Research Support, Non-U.S. Gov't Review MeSH terms
A Better Alternative to Phthalates? | NIST
However, phthalates can disrupt the hormonal or endocrine system, which may cause pregnancy loss, infertility and harmful effects on the delivery of a baby. As a result, many manufacturers have replaced phthalates with chemicals such as DINCH, another type of plasticizer, but less is known about the effects of this chemical compound on humans.
[Toxicity effects of phthalate substitute plasticizers used
Alkyl esters of phthalic acid, such as di- (2-ethylhe xyl) phthalate, are commonly used as plasticizers in polyvinyl chloride and other plastics. They may constitute 2040% of the weight of the
Toxicological assessment of phthalates and their alternatives
Recently, there have been numerous reports showing that phthalates have negative health impacts such as asthma, breast cancer, obesity, type II diabetes, and male infertility. Due to these effects, there is an urgent need for phthalate alternatives.
- Are phthalate esters toxic?
- [Toxicity effects of phthalate substitute plasticizers used in toys] Phthalate esters are widely used as plasticizers in polyvinyl chloride products.
- Are alternative phthalate plasticizers toxic?
- Most long-term DNELs of alternative plasticizers are relatively high compared to DEHP (one of the most toxic phthalate plasticizers). Also other phthalates (DINP, DIDP, DPHP) were less toxic than DEHP, having higher DNELs. For DBA, COMGHA, DOS and DBS no hazard was identified due to the extremely low toxicities measured.
- What is plasticizer phthalate?
- Plasticizer phthalate is a pollutant. Its teratogenic or carcinogenic effects on human. Phytotoxic effects of phthalate and its transmission through food chain. Abatement of phthalate via bioremediation. Microbe-mediated soil-phthalate bioaugmentation approaches.
- Do alternative plasticizers metabolize phthalates and DINCH?
- For instance, the human metabolism of phthalates and DINCH is well known. Therefore, exposure to these substances can be well assessed by measuring relevant metabolites in human matrices like blood or urine. Unfortunately, this has not been done for all relevant alternative plasticizers.
- Are alternative plasticizers phthalate or phosphate esters?
- Additionally, some substances are not exclusively being used as plasticizers. For example, phosphate esters have also been widely used as flame retardants (Marklund et al., 2003, Wei et al., 2015). In this work, we consider the term “alternative plasticizer” as a synonym for non-phthalate plasticizers.
- Does phthalate cause obesity?
- Various studies have linked phthalate exposure to obesity, including one study showing the exposure of LMWP to be associated with obesity in male children, as well as HMWP exposure to obesity in all adult groups.
